Noncontact photoacoustic tomography imaging using a low-coherence interferometer with rapid detection of phase modulation

Jun Liu; Zhilie Tang; Hongchun Tang; Yongbo Wu; Yi Wang

doi:10.1117/12.2068704

17 September 2014 Noncontact photoacoustic tomography imaging using a low-coherence interferometer with rapid detection of phase modulation

Jun Liu, Zhilie Tang, Hongchun Tang, Yongbo Wu, Yi Wang

Author Affiliations +

Proceedings Volume 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014); 92301P (2014) https://doi.org/10.1117/12.2068704
Event: Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014), 2014, Wuhan, China

Abstract

A photoacoustic tomography imaging system using a low-coherence interferometer with rapid detection of phase modulation was designed, fabricated, and tested for biologic imaging. A noncontact probing technique was applied to improve the practicability of the system. The technique is experimentally verified by the image of a simulated tissue sample and the blood vessels within a mouse ear flap (pinna) in vivo. The system’s axial and lateral resolutions are evaluated at 45 and ~15 μm, respectively. The system’s imaging depth is 1mm in a special phantom. The results show that the system has the feasibility to be used as a photoacoustic tomography imaging method, and it may provide a kind of possibility of noncontact real-time PAT.

Citation Download Citation

Jun Liu, Zhilie Tang, Hongchun Tang, Yongbo Wu, and Yi Wang "Noncontact photoacoustic tomography imaging using a low-coherence interferometer with rapid detection of phase modulation", Proc. SPIE 9230, Twelfth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2014), 92301P (17 September 2014); https://doi.org/10.1117/12.2068704

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KEYWORDS

Signal detection

Photoacoustic tomography

Interferometers

Imaging systems

Acquisition tracking and pointing

Photoacoustic spectroscopy

Photoacoustic imaging

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