An overview of alignment issues for in-vivo image guided proton therapy

Benoit Macq; Jonathan Orban de Xivry

doi:10.1117/12.2074783

28 January 2015 An overview of alignment issues for in-vivo image guided proton therapy

Benoit Macq, Jonathan Orban de Xivry

Proceedings Volume 9287, 10th International Symposium on Medical Information Processing and Analysis; 92870S (2015) https://doi.org/10.1117/12.2074783
Event: Tenth International Symposium on Medical Information Processing and Analysis, 2014, Cartagena de Indias, Colombia

Abstract

Protontherapy is based on physical properties of ion beams which allow the delivery of high radiation doses at very precise location in the body of the patient. The treatment planning aims at maximizing the delivery in the target volume while avoiding any organs at risk. The treatment is generally planned prior the treatment, and the patient is aligned in the treatment room on the basis of fiducial markers. However, the alignment of the patient may suffer from lack of precision and moreover, the body of the patient may vary between the time of imaging for planning and the time of treatment in the protontherapy room. More precise protontherapy and adaptive treatment which can track modifications of the body and the treatment of mobile tumors require the design of in vivo imaging systems to be deployed in the treatment room. The goal of this paper is to overview the present and future development of in-vivo image guided protontherapy and to give some image processing related challenges. The technique mostly used today is to take 2 orthogonal X-ray views of the patient. It requires an efficient 2D-3D coregistration procedure but is quite easy to deploy. Cone Beam CT is a next step which allows the capture of an in-vivo 3-D view on which the 3-D planning can be registered. The ultimate goal is to develop 4-D imaging techniques suited for the treatment of mobile tumors, for the cases of lung cancer. The development of new detectors will allow to validate the treatment by an “a posteriori” validation of the dose delivery in the body.

Citation Download Citation

Benoit Macq and Jonathan Orban de Xivry "An overview of alignment issues for in-vivo image guided proton therapy", Proc. SPIE 9287, 10th International Symposium on Medical Information Processing and Analysis, 92870S (28 January 2015); https://doi.org/10.1117/12.2074783

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

In vivo imaging

Tumors

3D image processing

X-ray computed tomography

Computed tomography

Lung cancer

Imaging systems

Show All Keywords

Keywords/Phrases

Search In:

Publication Years