Pancreas segmentation from 3D abdominal CT images using patient-specific weighted subspatial probabilistic atlases

Kenichi Karasawa; Masahiro Oda; Yuichiro Hayashi; Yukitaka Nimura; Takayuki Kitasaka; Kazunari Misawa; Michitaka Fujiwara M.D.; Daniel Rueckert; Kensaku Mori

doi:10.1117/12.2081756

20 March 2015 Pancreas segmentation from 3D abdominal CT images using patient-specific weighted subspatial probabilistic atlases

Kenichi Karasawa, Masahiro Oda, Yuichiro Hayashi, Yukitaka Nimura, Takayuki Kitasaka, Kazunari Misawa, Michitaka Fujiwara M.D., Daniel Rueckert, Kensaku Mori

Author Affiliations +

Proceedings Volume 9413, Medical Imaging 2015: Image Processing; 94131A (2015) https://doi.org/10.1117/12.2081756
Event: SPIE Medical Imaging, 2015, Orlando, Florida, United States

Abstract

Abdominal organ segmentations from CT volumes are now widely used in the computer-aided diagnosis and surgery assistance systems. Among abdominal organs, the pancreas is especially difficult to segment because of its large individual differences of the shape and position. In this paper, we propose a new pancreas segmentation method from 3D abdominal CT volumes using patient-specific weighted-subspatial probabilistic atlases. First of all, we perform normalization of organ shapes in training volumes and an input volume. We extract the Volume Of Interest (VOI) of the pancreas from the training volumes and an input volume. We divide each training VOI and input VOI into some cubic regions. We use a nonrigid registration method to register these cubic regions of the training VOI to corresponding regions of the input VOI. Based on the registration results, we calculate similarities between each cubic region of the training VOI and corresponding region of the input VOI. We select cubic regions of training volumes having the top N similarities in each cubic region. We subspatially construct probabilistic atlases weighted by the similarities in each cubic region. After integrating these probabilistic atlases in cubic regions into one, we perform a rough-to-precise segmentation of the pancreas using the atlas. The results of the experiments showed that utilization of the training volumes having the top N similarities in each cubic region led good results of the pancreas segmentation. The Jaccard Index and the average surface distance of the result were 58.9% and 2.04mm on average, respectively.

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Kenichi Karasawa, Masahiro Oda, Yuichiro Hayashi, Yukitaka Nimura, Takayuki Kitasaka, Kazunari Misawa, Michitaka Fujiwara M.D., Daniel Rueckert, and Kensaku Mori "Pancreas segmentation from 3D abdominal CT images using patient-specific weighted subspatial probabilistic atlases", Proc. SPIE 9413, Medical Imaging 2015: Image Processing, 94131A (20 March 2015); https://doi.org/10.1117/12.2081756

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