Preliminary results of non-contact THz imaging of cornea

Shijun Sung; James Garritano; Neha Bajwa; Sophie Deng; Jean-Pierre Hubschman; Warren S. Grundfest M.D.; Zachary D. Taylor

doi:10.1117/12.2086866

28 April 2015 Preliminary results of non-contact THz imaging of cornea

Shijun Sung, James Garritano, Neha Bajwa, Sophie Deng, Jean-Pierre Hubschman, Warren S. Grundfest M.D., Zachary D. Taylor

Author Affiliations +

Proceedings Volume 9362, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications VIII; 93620C (2015) https://doi.org/10.1117/12.2086866
Event: SPIE OPTO, 2015, San Francisco, California, United States

Abstract

This paper presents a novel THz optical design that allows the acquisition of THz reflectivity maps of in vivo cornea without the need for a field flattening window and preliminary imaging results of in vivo rabbit cornea. The system’s intended use is to sense small changes in corneal tissue water content (CTWC) that can be precursors for a host of diseases and pathologies. Unique beam optics allows the scanning of a curved surface at normal incidence while keeping the source detector and target stationary. Basic system design principles are discussed and image sets of spherical calibration targets and corneal phantom models are presented. The presented design will enable, for the first time, non-contact THz imaging of animal and human cornea.

Citation Download Citation

Shijun Sung, James Garritano, Neha Bajwa, Sophie Deng, Jean-Pierre Hubschman, Warren S. Grundfest M.D., and Zachary D. Taylor "Preliminary results of non-contact THz imaging of cornea", Proc. SPIE 9362, Terahertz, RF, Millimeter, and Submillimeter-Wave Technology and Applications VIII, 93620C (28 April 2015); https://doi.org/10.1117/12.2086866

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