Laser-wakefield accelerators for medical phase contrast imaging: Monte Carlo simulations and experimental studies

S. Cipiccia; D. Reboredo; Fabio A. Vittoria; G. H. Welsh; P. Grant; D. W. Grant; E. Brunetti; S. M. Wiggins; A. Olivo; D. A. Jaroszynski

doi:10.1117/12.2178837

14 May 2015 Laser-wakefield accelerators for medical phase contrast imaging: Monte Carlo simulations and experimental studies

S. Cipiccia, D. Reboredo , Fabio A. Vittoria, G. H. Welsh, P. Grant, D. W. Grant, E. Brunetti, S. M. Wiggins, A. Olivo, D. A. Jaroszynski

Author Affiliations +

Proceedings Volume 9514, Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles III; 951417 (2015) https://doi.org/10.1117/12.2178837
Event: SPIE Optics + Optoelectronics, 2015, Prague, Czech Republic

Abstract

X-ray phase contrast imaging (X-PCi) is a very promising method of dramatically enhancing the contrast of X-ray images of microscopic weakly absorbing objects and soft tissue, which may lead to significant advancement in medical imaging with high-resolution and low-dose. The interest in X-PCi is giving rise to a demand for effective simulation methods. Monte Carlo codes have been proved a valuable tool for studying X-PCi including coherent effects. The laser-plasma wakefield accelerators (LWFA) is a very compact particle accelerator that uses plasma as an accelerating medium. Accelerating gradient in excess of 1 GV/cm can be obtained, which makes them over a thousand times more compact than conventional accelerators. LWFA are also sources of brilliant betatron radiation, which are promising for applications including medical imaging. We present a study that explores the potential of LWFA-based betatron sources for medical X-PCi and investigate its resolution limit using numerical simulations based on the FLUKA Monte Carlo code, and present preliminary experimental results.

Citation Download Citation

S. Cipiccia, D. Reboredo , Fabio A. Vittoria, G. H. Welsh, P. Grant, D. W. Grant, E. Brunetti, S. M. Wiggins, A. Olivo, and D. A. Jaroszynski "Laser-wakefield accelerators for medical phase contrast imaging: Monte Carlo simulations and experimental studies", Proc. SPIE 9514, Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles III, 951417 (14 May 2015); https://doi.org/10.1117/12.2178837

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
5 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Monte Carlo methods

Phase contrast

X-rays

Plasma

X-ray imaging

Electrons

Medical imaging

Show All Keywords

Keywords/Phrases

Search In:

Publication Years