Cartilage analysis by reflection spectroscopy

T. Laun; M. Muenzer; U. Wenzel; S. Princz; M. Hessling

doi:10.1117/12.2196660

15 July 2015 Cartilage analysis by reflection spectroscopy

T. Laun, M. Muenzer, U. Wenzel, S. Princz, M. Hessling

Proceedings Volume 9537, Clinical and Biomedical Spectroscopy and Imaging IV; 95372B (2015) https://doi.org/10.1117/12.2196660
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

A cartilage bioreactor with analytical functions for cartilage quality monitoring is being developed. For determining cartilage composition, reflection spectroscopy in the visible (VIS) and near infrared (NIR) spectral region is evaluated. Main goal is the determination of the most abundant cartilage compounds water, collagen I and collagen II. Therefore VIS and NIR reflection spectra of different cartilage samples of cow, pig and lamb are recorded. Due to missing analytical instrumentation for identifying the cartilage composition of these samples, typical literature concentration values are used for the development of chemometric models.

In spite of these limitations the chemometric models provide good cross correlation results for the prediction of collagen I and II and water concentration based on the visible and the NIR reflection spectra.

Citation Download Citation

T. Laun, M. Muenzer, U. Wenzel, S. Princz, and M. Hessling "Cartilage analysis by reflection spectroscopy", Proc. SPIE 9537, Clinical and Biomedical Spectroscopy and Imaging IV, 95372B (15 July 2015); https://doi.org/10.1117/12.2196660

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