Sensor structure concepts for the analysis or local radiation exposure of biological samples at terahertz and millimeter wave frequencies

Fabian Dornuf; Roland Dörr; David Lämmle; Helmut F. Schlaak; Viktor Krozer

doi:10.1117/12.2205583

7 March 2016 Sensor structure concepts for the analysis or local radiation exposure of biological samples at terahertz and millimeter wave frequencies

Fabian Dornuf, Roland Dörr, David Lämmle, Helmut F. Schlaak, Viktor Krozer

Author Affiliations +

Proceedings Volume 9706, Optical Interactions with Tissue and Cells XXVII; 97061U (2016) https://doi.org/10.1117/12.2205583
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We have studied several sensor concepts for biomedical applications operating in the millimeter wave and terahertz range. On one hand, rectangular waveguide structure were designed and extended with microfluidic channels. In this way a simple analysis of aqueous solutions at various waveguide bands is possible. In our case, we focused on the frequency range between 75 GHz and 110 GHz. On the other hand, planar sensor structures for aqueous solutions have been developed based on coplanar waveguides. With these planar sensors it is possible to concentrate the interaction volume on small sensor areas, which achieve a local exposure of the radiation to the sample. When equipping the sensor with microfluidic structures the sample volume could be reduced significantly and enabled a localized interaction with the sensor areas. The sensors are designed to exhibit a broadband behavior up to 300 GHz. Narrow-band operation can also be achieved for potentially increased sensitivity by using resonant structures. Several tests with Glucose dissolved in water show promising results for the distinction of different glucose levels at millimeter wave frequencies. The planar structures can also be used for the exposure of biological cells or cell model systems like liposomes with electromagnetic radiation. Several studies are planned to distinguish on one hand the influence of millimeter wave exposure on biological systems and also to have a spectroscopic method which enables the analysis of cell processes, like membrane transport processes, with millimeter wave and terahertz frequencies by focusing the electric field directly on the analyzing sample.

Citation Download Citation

Fabian Dornuf, Roland Dörr, David Lämmle, Helmut F. Schlaak, and Viktor Krozer "Sensor structure concepts for the analysis or local radiation exposure of biological samples at terahertz and millimeter wave frequencies", Proc. SPIE 9706, Optical Interactions with Tissue and Cells XXVII, 97061U (7 March 2016); https://doi.org/10.1117/12.2205583

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Sensors

Waveguides

Glucose

Biological research

Extremely high frequency

Terahertz radiation

Microfluidics

Show All Keywords

Keywords/Phrases

Search In:

Publication Years