Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices

Kathy Beaudette; William Lo; Martin Villiger; Milen Shishkov; Nicolas Godbout; Brett E. Bouma; Caroline Boudoux

doi:10.1117/12.2209382

7 March 2016 Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices

Kathy Beaudette, William Lo, Martin Villiger, Milen Shishkov, Nicolas Godbout, Brett E. Bouma, Caroline Boudoux

Author Affiliations +

Proceedings Volume 9701, Multimodal Biomedical Imaging XI; 97010B (2016) https://doi.org/10.1117/12.2209382
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

There is a strong clinical need for an optical coherence tomography (OCT) system capable of delivering concurrent coagulation light enabling image-guided dynamic laser marking for targeted collection of biopsies, as opposed to a random sampling, to reduce false-negative findings. Here, we present a system based on double-clad fiber (DCF) capable of delivering pulsed laser light through the inner cladding while performing OCT through the core. A previously clinically validated commercial OCT system (NVisionVLE, Ninepoint Medical) was adapted to enable in vivo esophageal image-guided dynamic laser marking. An optimized DCF coupler was implemented into the system to couple both modalities into the DCF. A DCF-based rotary joint was used to couple light to the spinning DCF-based catheter for helical scanning. DCF-based OCT catheters, providing a beam waist diameter of 62μm at a working distance of 9.3mm, for use with a 17-mm diameter balloon sheath, were used for ex vivo imaging of a swine esophagus. Imaging results using the DCF-based clinical system show an image quality comparable with a conventional system with minimal crosstalk-induced artifacts. To further optimize DCF catheter optical design in order to achieve single-pulse marking, a Zemax model of the DCF output and its validation are presented.

Citation Download Citation

Kathy Beaudette, William Lo, Martin Villiger, Milen Shishkov, Nicolas Godbout, Brett E. Bouma, and Caroline Boudoux "Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices", Proc. SPIE 9701, Multimodal Biomedical Imaging XI, 97010B (7 March 2016); https://doi.org/10.1117/12.2209382

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