Optical topography guided semi-three-dimensional diffuse optical tomography for a multi-layer model of occipital cortex: a pilot methodological study

Hao Ding; Yao Zhang; Jie He; Huijuan Zhao; Feng Gao

doi:10.1117/12.2209002

8 March 2016 Optical topography guided semi-three-dimensional diffuse optical tomography for a multi-layer model of occipital cortex: a pilot methodological study

Hao Ding, Yao Zhang, Jie He, Huijuan Zhao, Feng Gao

Author Affiliations +

Proceedings Volume 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation; 96901S (2016) https://doi.org/10.1117/12.2209002
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

In this paper, an optical topography (OT) guided diffuse optical tomography (DOT) scheme is developed for functional imaging of the occipital cortex. The method extends the previously proposed semi-three-dimensional DOT methodology to reconstruction of two-dimensional extracerebral and cerebral images using a visual cortex oriented five-layered slab geometry, and incorporate the OT localization regularization in the cerebral reconstruction to achieve enhanced quantitative accuracy and spatial resolution. We validate the methodology using simulated data and demonstrate its merits in comparison to the standalone OT and DOT.

Citation Download Citation

Hao Ding, Yao Zhang, Jie He, Huijuan Zhao, and Feng Gao "Optical topography guided semi-three-dimensional diffuse optical tomography for a multi-layer model of occipital cortex: a pilot methodological study", Proc. SPIE 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, 96901S (8 March 2016); https://doi.org/10.1117/12.2209002

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available