High frame rate photoacoustic imaging using clinical ultrasound system

Kathyayini Sivasubramanian; Manojit Pramanik

doi:10.1117/12.2209037

15 March 2016 High frame rate photoacoustic imaging using clinical ultrasound system

Kathyayini Sivasubramanian, Manojit Pramanik

Proceedings Volume 9708, Photons Plus Ultrasound: Imaging and Sensing 2016; 97084Q (2016) https://doi.org/10.1117/12.2209037
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Photoacoustic tomography (PAT) is a potential hybrid imaging modality which is gaining attention in the field of medical imaging. Typically a Q-switched Nd:YAG laser is used to excite the tissue and generate photoacoustic signals. But, they are not suitable for clinical applications owing to their high cost, large size. Also, their low pulse repetition rate (PRR) of few tens of hertz prevents them from being used in real-time PAT. So, there is a growing need for an imaging system capable of real-time imaging for various clinical applications. In this work, we are using a nanosecond pulsed laser diode as an excitation source and a clinical ultrasound imaging system to obtain the photoacoustic imaging. The excitation laser is ~803 nm in wavelength with energy of ~1.4 mJ per pulse. So far, the reported frame rate for photoacoustic imaging is only a few hundred Hertz. We have demonstrated up to 7000 frames per second framerate in photoacoustic imaging (B-mode) and measured the flow rate of fast moving obje ct. Phantom experiments were performed to test the fast imaging capability and measure the flow rate of ink solution inside a tube. This fast photoacoustic imaging can be used for various clinical applications including cardiac related problems, where the blood flow rate is quite high, or other dynamic studies.

Citation Download Citation

Kathyayini Sivasubramanian and Manojit Pramanik "High frame rate photoacoustic imaging using clinical ultrasound system", Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97084Q (15 March 2016); https://doi.org/10.1117/12.2209037

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