Investigating relationships between left atrial volume, symmetry, and sphericity

Prahlad G. Menon; Sotiris Nedios; Gerhard Hindricks; Andreas Bollmann

doi:10.1117/12.2216491

29 March 2016 Investigating relationships between left atrial volume, symmetry, and sphericity

Prahlad G. Menon, Sotiris Nedios, Gerhard Hindricks, Andreas Bollmann

Proceedings Volume 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging; 97882J (2016) https://doi.org/10.1117/12.2216491
Event: SPIE Medical Imaging, 2016, San Diego, California, United States

Abstract

Catheter ablation is a safe and effective therapy for drug-refractory patients symptomatic of atrial fibrillation (AF), with up to 80% of patients experiencing long-term arrhythmia-free survival. However, up to 20–40% of patients require more than one procedure in order to become arrhythmia-free. Therefore, appropriate patient selection is paramount to the effective implementation and long-term success of ablation therapy for patients with atrial fibrillation (AF). In this study, as a precursor to evaluating clinical significance of specific LA shape metrics as pre-procedural predictors of AF recurrence following ablative pulmonary vein isolation therapy, we report on a computational geometric analysis in a pilot cohort evaluating relationships between various patient-specific metrics of LA shape which might have such predictive value. This study specifically is focused on establishing the relationship between LA volume and sphericity, using a novel methodology for computing atrial sphericity based on regional shape.

Citation Download Citation

Prahlad G. Menon, Sotiris Nedios, Gerhard Hindricks, and Andreas Bollmann "Investigating relationships between left atrial volume, symmetry, and sphericity", Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 97882J (29 March 2016); https://doi.org/10.1117/12.2216491

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