In vivo small animal lung speckle imaging with a benchtop in-line XPC system

A. B. Garson III; S. Gunsten; S. Vasireddi; S. Brody; M. A. Anastasio

doi:10.1117/12.2217267

1 April 2016 In vivo small animal lung speckle imaging with a benchtop in-line XPC system

A. B. Garson III, S. Gunsten, S. Vasireddi, S. Brody, M. A. Anastasio

Proceedings Volume 9783, Medical Imaging 2016: Physics of Medical Imaging; 97834Z (2016) https://doi.org/10.1117/12.2217267
Event: SPIE Medical Imaging, 2016, San Diego, California, United States

Abstract

X-ray phase-contrast (XPC) images of mouse lungs were acquired in vivo with a benchtop XPC system employing a conventional microfocus source. A strong speckled intensity pattern was present in lung regions of the XPC radiographs, previously only observed in synchroton experiments and in situ benchtop studies. We showed how the texture characteristics of the speckle is influenced by the amount of air present in the lungs at different points in the breathing cycle.

Citation Download Citation

A. B. Garson III, S. Gunsten, S. Vasireddi, S. Brody, and M. A. Anastasio "In vivo small animal lung speckle imaging with a benchtop in-line XPC system", Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97834Z (1 April 2016); https://doi.org/10.1117/12.2217267

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