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27 April 2016 Depth-resolved incoherent and coherent wide-field high-content imaging (Conference Presentation)
Peter T. So
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Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI; 971205 (2016) https://doi.org/10.1117/12.2217744
Event: SPIE BiOS, 2016, San Francisco, California, United States
Abstract
Recent advances in depth-resolved wide-field imaging technique has enabled many high throughput applications in biology and medicine. Depth resolved imaging of incoherent signals can be readily accomplished with structured light illumination or nonlinear temporal focusing. The integration of these high throughput systems with novel spectroscopic resolving elements further enable high-content information extraction. We will introduce a novel near common-path interferometer and demonstrate its uses in toxicology and cancer biology applications. The extension of incoherent depth-resolved wide-field imaging to coherent modality is non-trivial. Here, we will cover recent advances in wide-field 3D resolved mapping of refractive index, absorbance, and vibronic components in biological specimens.
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View presentation recording on the SPIE Digital Library: http://dx.doi.org/10.1117/12.2217744.4848767236001
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Peter T. So "Depth-resolved incoherent and coherent wide-field high-content imaging (Conference Presentation)", Proc. SPIE 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 971205 (27 April 2016); https://doi.org/10.1117/12.2217744
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KEYWORDS
Coherence imaging
Biology
Cancer
Information fusion
Interferometers
Medicine
Nonlinear optics
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