Towards low cost photoacoustic Microscopy system for evaluation of skin health

Ali Hariri; Afreen Fatima; Nafiseh Mohammadian; Nicholas Bely; Mohammadreza Nasiriavanaki

doi:10.1117/12.2238423

19 September 2016 Towards low cost photoacoustic Microscopy system for evaluation of skin health

Ali Hariri, Afreen Fatima, Nafiseh Mohammadian, Nicholas Bely, Mohammadreza Nasiriavanaki

Proceedings Volume 9976, Imaging Spectrometry XXI; 99760X (2016) https://doi.org/10.1117/12.2238423
Event: SPIE Optical Engineering + Applications, 2016, San Diego, California, United States

Abstract

Photoacoustic imaging (PAI) involves both optical and ultrasound imaging, owing to this combination the system is capable of generating high resolution images with good penetration depth. With the growing applications of PAI in neurology, vascular biology, dermatology, ophthalmology, tissue engineering, angiogenesis etc., there is a need to make the system more compact, cheap and effective. Therefore we designed an economical and compact version of PAI systems by replacing expensive and sophisticated lasers with a robust pulsed laser diode of 905 nm wavelength. In this study, we determine the feasibility of the Photoacoustic imaging with a very low excitation energy of 0.1uJ in Photoacoustic microscopy. We developed a low cost portable Photoacoustic Imaging including microscopy (both reflection) Phantom study was performed in this configuration and also ex-vivo image was obtained from mouse skin.

Citation Download Citation

Ali Hariri, Afreen Fatima, Nafiseh Mohammadian, Nicholas Bely, and Mohammadreza Nasiriavanaki "Towards low cost photoacoustic Microscopy system for evaluation of skin health", Proc. SPIE 9976, Imaging Spectrometry XXI, 99760X (19 September 2016); https://doi.org/10.1117/12.2238423

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