Dual-wavelength retinal image registration based on vessel segmentation and optic disc detection

Yong-li Xian; Yun Dai; Chun-ming Gao; Rui Du

doi:10.1117/12.2243587

27 September 2016 Dual-wavelength retinal image registration based on vessel segmentation and optic disc detection

Yong-li Xian, Yun Dai, Chun-ming Gao, Rui Du

Proceedings Volume 9684, 8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test, Measurement Technology, and Equipment; 968417 (2016) https://doi.org/10.1117/12.2243587
Event: Eighth International Symposium on Advanced Optical Manufacturing and Testing Technology (AOMATT2016), 2016, Suzhou, China

Abstract

The dual-wavelength retinal image registration is one of the critical steps in the spectrophotometric measurements of oxygen saturation in the retinal vasculature. The dual-wavelength images (570 nm and 600 nm) are simultaneously captured by dual-wavelength retinal oximeter based on commercial fundus camera. The retinal oxygen saturation is finally measured after vessel segmentation, image registration and calculation of optical density ratio of the two images. Because the dual-wavelength images are acquired from different optical path, it is necessary to go through image registration before they are used to analyze the oxygen saturation. This paper presents a new approach to dual-wavelength retinal image registration based on vessel segmentation and optic disc detection. Firstly, the multi-scale segmentation algorithm based on the Hessian matrix is used to realize vessel segmentation. Secondly, after optic disc is detected by convergence index filter and the center of the optic disc is obtained by centriod algorithm, the translational difference between the images can be determined. The center of the optic disc is used as the center of rotation, and the registration based on mutual information can be achieved using contour and gray information of vessels through segmented image. So the rotational difference between the images can be determined too. The result shows that the algorithm can provide an accurate registration for the dual-wavelength retinal image.

Citation Download Citation

Yong-li Xian, Yun Dai, Chun-ming Gao, and Rui Du "Dual-wavelength retinal image registration based on vessel segmentation and optic disc detection", Proc. SPIE 9684, 8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optical Test, Measurement Technology, and Equipment, 968417 (27 September 2016); https://doi.org/10.1117/12.2243587

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available