Porous silicon biosensor for Echinococcosis detection based on fluorescence spectroscopy

Xiaoyi Lv; Jiaqing Mo; Zhenhong Jia

doi:10.1117/12.2243784

25 October 2016 Porous silicon biosensor for Echinococcosis detection based on fluorescence spectroscopy

Xiaoyi Lv, Jiaqing Mo, Zhenhong Jia

Proceedings Volume 9686, 8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optoelectronic Materials and Devices; 96861H (2016) https://doi.org/10.1117/12.2243784
Event: Eighth International Symposium on Advanced Optical Manufacturing and Testing Technology (AOMATT2016), 2016, Suzhou, China

Abstract

Agriculture and animal husbandry area, such as Xinjiang, has high rates of hydatid disease. Protein P38 of Echinococcus granulosus has practical value in diagnosis of hydatid disease, and it may be used as a diagnostic marker and a prognostic index. In recent years, the development of biosensors based on porous silicon has been developed rapidly. In this experiment, the protein P38 detection based on fluorescence changes of porous silicon following protein P38 molecule adsorption. The results of the tests indicated that, with the increase of antigen concentration, the fluorescence decrease of porous silicon is also increasing. It is provided the foundation for the basic research of the molecular mechanism of P38, and diagnosis and treatment of cystic echinococcosis.

Citation Download Citation

Xiaoyi Lv, Jiaqing Mo, and Zhenhong Jia "Porous silicon biosensor for Echinococcosis detection based on fluorescence spectroscopy", Proc. SPIE 9686, 8th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Optoelectronic Materials and Devices, 96861H (25 October 2016); https://doi.org/10.1117/12.2243784

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