In vivo hyperspectral imaging and differentiation of skin cancer

Larisa A. Zherdeva; Ivan A. Bratchenko; Oleg O. Myakinin; Alexander A. Moryatov; Sergey V. Kozlov; Valery P. Zakharov

doi:10.1117/12.2246433

31 October 2016 In vivo hyperspectral imaging and differentiation of skin cancer

Larisa A. Zherdeva, Ivan A. Bratchenko, Oleg O. Myakinin, Alexander A. Moryatov, Sergey V. Kozlov, Valery P. Zakharov

Proceedings Volume 10024, Optics in Health Care and Biomedical Optics VII; 100244G (2016) https://doi.org/10.1117/12.2246433
Event: SPIE/COS Photonics Asia, 2016, Beijing, China

Abstract

Results of hyperspectral imaging analysis for in vivo visualization of skin neoplasms are presented. 16 melanomas, 19 basal cell carcinomas and 10 benign tumors with different stages of neoplasm growth were tested. The HSI system provide skin tissue images with 5 nm spectral resolution in the range of 450-750 nm with automatic stabilization of each frame compensating displacement of the scanning area due to spontaneous macro-movements of the patient. The integrated optical densities in 530-600 and 600-670 nm ranges are used for real-time hemoglobin and melanin distribution imaging in skin tissue. It was shown that the total accuracy of skin cancer identification exceeds 90% and 70% for differentiation of melanomas from BCC and begihn tumors. It was demonstrated the possibility for HSI classification of melanomas of different stages.

Citation Download Citation

Larisa A. Zherdeva, Ivan A. Bratchenko, Oleg O. Myakinin, Alexander A. Moryatov, Sergey V. Kozlov, and Valery P. Zakharov "In vivo hyperspectral imaging and differentiation of skin cancer", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100244G (31 October 2016); https://doi.org/10.1117/12.2246433

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