Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism

Kohji Mitsubayashi; Po-Jen Chien; Ming Ye; Takuma Suzuki; Koji Toma; Takahiro Arakawa

doi:10.1117/12.2244660

24 November 2016 Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism

Kohji Mitsubayashi, Po-Jen Chien, Ming Ye, Takuma Suzuki, Koji Toma, Takahiro Arakawa

Author Affiliations +

Proceedings Volume 10013, SPIE BioPhotonics Australasia; 100131T (2016) https://doi.org/10.1117/12.2244660
Event: SPIE BioPhotonics Australasia, 2016, Adelaide, Australia

Abstract

A fluorometric acetone biosniffer (biochemical gas sensor) for assessment of lipid metabolism utilizing reverse reaction of secondary alcohol dehydrogenase was constructed and evaluated. The biosniffer showed highly sensitivity and selectivity for continuous monitoring of gaseous acetone. The measurement of breath acetone concentration during fasting and aerobic exercise were also investigated. The acetone biosniffer provides a novel analytical tool for noninvasive evaluation of human lipid metabolism and it is also expected to use for the clinical and physiological applications such as monitoring the progression of diabetes.

Citation Download Citation

Kohji Mitsubayashi, Po-Jen Chien, Ming Ye, Takuma Suzuki, Koji Toma, and Takahiro Arakawa "Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism", Proc. SPIE 10013, SPIE BioPhotonics Australasia, 100131T (24 November 2016); https://doi.org/10.1117/12.2244660

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