Multiparameter thermo-mechanical OCT-based characterization of laser-induced cornea reshaping

Vladimir Yu. Zaitsev; Alexandr L. Matveyev; Lev A. Matveev; Grigory V. Gelikonov; Alex Vitkin; Alexander I. Omelchenko; Olga I. Baum; Dmitry V. Shabanov; Alexander A. Sovetsky; Emil N. Sobol

doi:10.1117/12.2253610

21 February 2017 Multiparameter thermo-mechanical OCT-based characterization of laser-induced cornea reshaping

Vladimir Yu. Zaitsev, Alexandr L. Matveyev, Lev A. Matveev, Grigory V. Gelikonov, Alex Vitkin, Alexander I. Omelchenko, Olga I. Baum, Dmitry V. Shabanov, Alexander A. Sovetsky, Emil N. Sobol

Author Affiliations +

Proceedings Volume 10067, Optical Elastography and Tissue Biomechanics IV; 100670V (2017) https://doi.org/10.1117/12.2253610
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Phase-sensitive optical coherence tomography (OCT) is used for visualizing dynamic and cumulative strains and corneashape changes during laser-produced tissue heating. Such non-destructive (non-ablative) cornea reshaping can be used as a basis of emerging technologies of laser vision correction. In experiments with cartilaginous samples, polyacrilamide phantoms and excised rabbit eyes we demonstrate ability of the developed OCT system to simultaneously characterize transient and cumulated strain distributions, surface displacements, scattering tissue properties and possibility of temperature estimation via thermal-expansion measurements. The proposed approach can be implemented in perspective real-time OCT systems for ensuring safety of new methods of laser reshaping of cornea.

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Vladimir Yu. Zaitsev, Alexandr L. Matveyev, Lev A. Matveev, Grigory V. Gelikonov, Alex Vitkin, Alexander I. Omelchenko, Olga I. Baum, Dmitry V. Shabanov, Alexander A. Sovetsky, and Emil N. Sobol "Multiparameter thermo-mechanical OCT-based characterization of laser-induced cornea reshaping", Proc. SPIE 10067, Optical Elastography and Tissue Biomechanics IV, 100670V (21 February 2017); https://doi.org/10.1117/12.2253610

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