Global microwave endometrial ablation for menorrhagia treatment

Hojjatollah Fallahi; Jan Šebek; Eric Frattura; Jessica Schenck; Punit Prakash

doi:10.1117/12.2254097

22 February 2017 Global microwave endometrial ablation for menorrhagia treatment

Hojjatollah Fallahi, Jan Šebek, Eric Frattura, Jessica Schenck, Punit Prakash

Proceedings Volume 10066, Energy-based Treatment of Tissue and Assessment IX; 100660K (2017) https://doi.org/10.1117/12.2254097
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Thermal ablation is a dominant therapeutic option for minimally invasive treatment of menorrhagia. Compared to other energy modalities for ablation, microwaves offer the advantages of conformal energy delivery to tissue within short times. The objective of endometrial ablation is to destroy the endometrial lining of the uterine cavity, with the clinical goal of achieving reduction in bleeding. Previous efforts have demonstrated clinical use of microwaves for endometrial ablation. A considerable shortcoming of most systems is that they achieve ablation of the target by translating the applicator in a point-to-point fashion. Consequently, treatment outcome may be highly dependent on physician skill. Global endometrial ablation (GEA) not only eliminates this operator dependence and simplifies the procedure but also facilitates shorter and more reliable treatments. The objective of our study was to investigate antenna structures and microwave energy delivery parameters to achieve GEA. Another objective was to investigate a method for automatic and reliable determination of treatment end-point. A 3D-coupled FEM electromagnetic and heat transfer model with temperature and frequency dependent material properties was implemented to characterize microwave GEA. The unique triangular geometry of the uterus where lateral narrow walls extend from the cervix to the fundus forming a wide base and access afforded through an endocervical approach limit the overall diameter of the final device. We investigated microwave antenna designs in a deployed state inside the uterus. The impact of ablation duration on treatment outcome was investigated. Prototype applicators were fabricated and experimentally evaluated in ex vivo tissue to verify the simulation results and demonstrate proof-of-concept.

Citation Download Citation

Hojjatollah Fallahi, Jan Šebek, Eric Frattura, Jessica Schenck, and Punit Prakash "Global microwave endometrial ablation for menorrhagia treatment", Proc. SPIE 10066, Energy-based Treatment of Tissue and Assessment IX, 100660K (22 February 2017); https://doi.org/10.1117/12.2254097

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available