Motion correction of dynamic contrast enhanced MRI of the liver

Mariëlle J. A. Jansen; Wouter B. Veldhuis; Maarten S. van Leeuwen; Josien P. W. Pluim

doi:10.1117/12.2253842

24 February 2017 Motion correction of dynamic contrast enhanced MRI of the liver

Mariëlle J. A. Jansen, Wouter B. Veldhuis, Maarten S. van Leeuwen, Josien P. W. Pluim

Proceedings Volume 10133, Medical Imaging 2017: Image Processing; 101331T (2017) https://doi.org/10.1117/12.2253842
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

Motion correction of dynamic contrast enhanced magnetic resonance images (DCE-MRI) is a challenging task, due to changes in image appearance. In this study a groupwise registration, using a principle component analysis (PCA) based metric, is evaluated for clinical DCE MRI of the liver. The groupwise registration transforms the images to a common space, rather than to a reference volume as conventional pairwise methods do, and computes the similarity metric on all volumes simultaneously. This groupwise registration method is compared to a pairwise approach using a mutual information metric. Clinical DCE MRI of the abdomen of eight patients were included. Per patient one lesion in the liver was manually segmented in all temporal images (N=16). The registered images were compared for accuracy, spatial and temporal smoothness after transformation, and lesion volume change. Compared to a pairwise method or no registration, groupwise registration provided better alignment. In our recently started clinical study groupwise registered clinical DCE MRI of the abdomen of nine patients were scored by three radiologists. Groupwise registration increased the assessed quality of alignment. The gain in reading time for the radiologist was estimated to vary from no difference to almost a minute. A slight increase in reader confidence was also observed. Registration had no added value for images with little motion. In conclusion, the groupwise registration of DCE MR images results in better alignment than achieved by pairwise registration, which is beneficial for clinical assessment.

Citation Download Citation

Mariëlle J. A. Jansen, Wouter B. Veldhuis, Maarten S. van Leeuwen, and Josien P. W. Pluim "Motion correction of dynamic contrast enhanced MRI of the liver", Proc. SPIE 10133, Medical Imaging 2017: Image Processing, 101331T (24 February 2017); https://doi.org/10.1117/12.2253842

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available