A biomechanical modeling guided simultaneous motion estimation and image reconstruction technique (SMEIR-Bio) for 4D-CBCT reconstruction

Xiaokun Huang; You Zhang; Jing Wang

doi:10.1117/12.2254524

9 March 2017 A biomechanical modeling guided simultaneous motion estimation and image reconstruction technique (SMEIR-Bio) for 4D-CBCT reconstruction

Xiaokun Huang, You Zhang, Jing Wang

Author Affiliations +

Proceedings Volume 10132, Medical Imaging 2017: Physics of Medical Imaging; 101322B (2017) https://doi.org/10.1117/12.2254524
Event: SPIE Medical Imaging, 2017, Orlando, Florida, United States

Abstract

Four-dimensional (4D) cone-beam computed tomography (CBCT) enables motion tracking of anatomical structures and removes artifacts introduced by motion. However, the imaging time/dose of 4D-CBCT is substantially longer/higher than traditional 3D-CBCT. We previously developed a simultaneous motion estimation and image reconstruction (SMEIR) algorithm, to reconstruct high-quality 4D-CBCT from limited number of projections to reduce the imaging time/dose. However, the accuracy of SMEIR is limited in reconstructing low-contrast regions with fine structure details. In this study, we incorporate biomechanical modeling into the SMEIR algorithm (SMEIR-Bio), to improve the reconstruction accuracy at low-contrast regions with fine details. The efficacy of SMEIR-Bio is evaluated using 11 lung patient cases and compared to that of the original SMEIR algorithm. Qualitative and quantitative comparisons showed that SMEIR-Bio greatly enhances the accuracy of reconstructed 4D-CBCT volume in low-contrast regions, which can potentially benefit multiple clinical applications including the treatment outcome analysis.

Citation Download Citation

Xiaokun Huang, You Zhang, and Jing Wang "A biomechanical modeling guided simultaneous motion estimation and image reconstruction technique (SMEIR-Bio) for 4D-CBCT reconstruction", Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101322B (9 March 2017); https://doi.org/10.1117/12.2254524

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