Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds

Mithun Kuniyil Ajith Singh; Vinay Parameshwarappa; Ellen Hendriksen; Wiendelt Steenbergen; Srirang Manohar

doi:10.1117/12.2252561

23 March 2017 Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds

Mithun Kuniyil Ajith Singh, Vinay Parameshwarappa, Ellen Hendriksen, Wiendelt Steenbergen, Srirang Manohar

Author Affiliations +

Proceedings Volume 10064, Photons Plus Ultrasound: Imaging and Sensing 2017; 100640G (2017) https://doi.org/10.1117/12.2252561
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

Reflection artifacts caused by the high signal from the optical fiber/ needle tip reflecting off the seed is an important problem in minimally invasive photoacoustic imaging of brachytherapy seeds. The presence of these artifacts confounds the interpretation of images and reduces contrast. We apply a new method called PAFUSion (Photoacoustic-guided focused ultrasound) to identify and reduce reflection artifacts generated in interstitial illumination imaging of brachytherapy seeds. We present the system comprising of a US imager and linear array, with illumination provided via a cutting needle. Non-radioactive brachytherapy seeds are implanted in a tissue mimicking phantom and ex vivo porcine tissue. The PAFUSion-corrected imaging results successfully demonstrate that our approach can identify and strongly reduce reflection artifacts in the context of photoacoustic needle. The phantom result also shows that multi-spectral photoacoustics can separate signals between the seeds and other optical absorbers.

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Citation Download Citation

Mithun Kuniyil Ajith Singh, Vinay Parameshwarappa, Ellen Hendriksen, Wiendelt Steenbergen, and Srirang Manohar "Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100640G (23 March 2017); https://doi.org/10.1117/12.2252561

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