Evaluation of blood microcirculation parameters by combined use of laser Doppler flowmetry and videocapillaroscopy methods

M. V. Volkov; D. A. Kostrova; N. B. Margaryants; I. P. Gurov; N. P. Erofeev; V. V. Dremin; E. V. Zharkikh; E. A. Zherebtsov; I. O. Kozlov; A. V. Dunaev

doi:10.1117/12.2267955

24 March 2017 Evaluation of blood microcirculation parameters by combined use of laser Doppler flowmetry and videocapillaroscopy methods

M. V. Volkov, D. A. Kostrova, N. B. Margaryants, I. P. Gurov, N. P. Erofeev, V. V. Dremin, E. V. Zharkikh, E. A. Zherebtsov, I. O. Kozlov, A. V. Dunaev

Author Affiliations +

Proceedings Volume 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII; 1033607 (2017) https://doi.org/10.1117/12.2267955
Event: Saratov Fall Meeting 2016: Fourth International Symposium on Optics and Biophotonics, 2016, Saratov, Russian Federation

Abstract

Laser Doppler flowmetry (LDF) is widely used for diagnosing blood microcirculation diseases. It is well known that the Doppler shift of laser radiation scattered by moving red blood cells (RBC) can be assessed through analyzing photocurrent produced by a photodetector. LDF signal contains information about regulating blood flow rhythms: myogenic, cardiac, nervous and endothelial. The method of videocapillaroscopy (VCS) allows local capillary blood flow velocity evaluation and, using video data processing algorithms, is able to assess RBC velocity changes into capillary. We present the results of simultaneous investigations of changes in tissue perfusion of the distal phalanx of human finger by the LDF as well as changes in capillary blood flow velocity in the nail bed evaluated by the VCS method during arterial occlusion test. The experimental results confirmed the correspondence between blood perfusion and blood flow velocity.

Citation Download Citation

M. V. Volkov, D. A. Kostrova, N. B. Margaryants, I. P. Gurov, N. P. Erofeev, V. V. Dremin, E. V. Zharkikh, E. A. Zherebtsov, I. O. Kozlov, and A. V. Dunaev "Evaluation of blood microcirculation parameters by combined use of laser Doppler flowmetry and videocapillaroscopy methods", Proc. SPIE 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII, 1033607 (24 March 2017); https://doi.org/10.1117/12.2267955

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available