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24 March 2017 In vitro destruction of anterior human lens capsule by submicrosecond pulses of Yb,Er:Glass laser
Andrey V. Belikov, Sergey V. Gagarsky, Andrey N. Sergeev, Sergey N. Smirnov
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Proceedings Volume 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII; 103360B (2017) https://doi.org/10.1117/12.2268800
Event: Saratov Fall Meeting 2016: Fourth International Symposium on Optics and Biophotonics, 2016, Saratov, Russian Federation
Abstract
The results of in vitro pilot study of anterior lens capsule destruction by submicrosecond pulses of Yb,Er:Glass laser as well as results of 2% agar gel damage threshold investigation are presented. It was established that the local destruction of anterior lens capsule is possible without any ruptures at energy densities up to 25 J/cm2 when exposed to 30 laser pulses, delivered via 200 μm optical quartz fiber. It was found that 2% agar gel damage threshold determined as minimal value of laser energy density required for appearance of the visually identifiable damage of agar gel decreases with the increase in the number of laser pulses. The 2% agar gel damage threshold on the air for a single laser pulse impact was about 2.3-3.3 J/cm2, for 5 pulses impact – about 1.8-2.5 J/cm2 and for 10 pulses impact – about 1.6-2.4 J/cm2.
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Andrey V. Belikov, Sergey V. Gagarsky, Andrey N. Sergeev, and Sergey N. Smirnov "In vitro destruction of anterior human lens capsule by submicrosecond pulses of Yb,Er:Glass laser", Proc. SPIE 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII, 103360B (24 March 2017); https://doi.org/10.1117/12.2268800
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KEYWORDS
Laser damage threshold
Fiber lasers
In vitro testing
Eye
Laser energy
Pulsed laser operation
Tissues
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