Ex-vivo imaging of blood and lymphatic vessels in conjunctiva using optical coherence tomography

Peijun Gong; Karol Karnowski; Paula Yu; Dong An; Dao-Yi Yu; David D. Sampson

doi:10.1117/12.2270180

29 April 2017 Ex-vivo imaging of blood and lymphatic vessels in conjunctiva using optical coherence tomography

Peijun Gong, Karol Karnowski, Paula Yu, Dong An, Dao-Yi Yu, David D. Sampson

Proceedings Volume 10340, International Conference on Biophotonics V; 1034018 (2017) https://doi.org/10.1117/12.2270180
Event: International Conference on Biophotonics V, 2017, Perth, Australia

Abstract

Label-free imaging of the blood and lymphatic vessel networks of the conjunctiva of the eye is important in assessing the drainage pathways affected by glaucoma. We utilize the characteristically low signal in optical coherence tomography (OCT) provided by such vessels in ex vivo tissue to characterize their morphology in two and three dimensions. We demonstrate this method on conjunctiva from six porcine eyes, showing the ready visualization of both vessel networks. Such ex vivo characterization is a necessary precursor for future in vivo studies directed towards improving glaucoma surgery.

Citation Download Citation

Peijun Gong, Karol Karnowski, Paula Yu, Dong An, Dao-Yi Yu, and David D. Sampson "Ex-vivo imaging of blood and lymphatic vessels in conjunctiva using optical coherence tomography", Proc. SPIE 10340, International Conference on Biophotonics V, 1034018 (29 April 2017); https://doi.org/10.1117/12.2270180

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