Nanophotonic interferometric immunosensors for label-free and real-time monitoring of chemical contaminants in marine environment

B. Chocarro-Ruiz; S. Herranz; A. Fernández Gavela; L. M. Lechuga

doi:10.1117/12.2256982

3 May 2017 Nanophotonic interferometric immunosensors for label-free and real-time monitoring of chemical contaminants in marine environment

B. Chocarro-Ruiz, S. Herranz, A. Fernández Gavela, L. M. Lechuga

Author Affiliations +

Proceedings Volume 10215, Advanced Environmental, Chemical, and Biological Sensing Technologies XIV; 1021503 (2017) https://doi.org/10.1117/12.2256982
Event: SPIE Commercial + Scientific Sensing and Imaging, 2017, Anaheim, CA, United States

Abstract

With the aim to prevent the oceans ecosystems degradation, there is an urgent need to develop portable sensing tools able to operate directly in the environment, avoiding the transportation of the ocean samples to analytical laboratories. To achieve this long-term objective, we describe here the work carried out to develop and characterize a multiplexed photonic immunosensor for the direct analysis of toxic chemical targets in marine samples. We have employed immunosensors based on photonic Bimodal Waveguide (BiMW) interferometric devices fabricated in silicon technologies combined with specific receptors and antibodies for the targeted chemical targets. Several procedures for the functionalization of the Si₃N₄ sensor surfaces have been evaluated based on wet silanization methods and further covalent receptor immobilization. The developed immunosensors, based on competitive inhibition assays, show LODs at μg/L or ng/L levels, depending on the analyzed chemical target.

Conference Presentation

Citation Download Citation

B. Chocarro-Ruiz, S. Herranz, A. Fernández Gavela, and L. M. Lechuga "Nanophotonic interferometric immunosensors for label-free and real-time monitoring of chemical contaminants in marine environment", Proc. SPIE 10215, Advanced Environmental, Chemical, and Biological Sensing Technologies XIV, 1021503 (3 May 2017); https://doi.org/10.1117/12.2256982

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available