There are several challenges when fibre image guides (FIG) are used for endoscopic speckle acquisition: cross talk between fibre cores, FIG fixed pattern noise, the small probe diameter and low sensitivity and resolution due to the decreased number of speckles and their low transmission through the FIG. In this paper, an endoscopic laser speckle contrast analysis system (ELASCA) based on a leached fibre image guide (LFIG) is presented. Different methods of acquiring LASCA images through LFIGs were investigated including the effect of changing the number of speckles per fibre, defocusing the FIG image onto the CCD and processing speckle images with masks and Butterworth filters to deal with the LFIG fixed pattern and noise from the cladding. The experimental results based on a phantom consisting of intralipid suspension pumped at varying speed showed that this system could detect speed changes and that in the case of multiple speckles per fibre the Nyquist frequency criterion need not be applied since the speckle may be transferred through the fibres to some extent. In contrast to the previously reported ELASCA results, this system can both give a map of the observed area and the temporal change in flow. An additional benefit is the small size of the LFIG, which is compatible with current endoscopic instrument channels and may allow additional surgical applications.© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.