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Proceedings Article

Theoretical and experimental comparison of tissue phantoms using white light spectroscopy

[+] Author Affiliations
Kaloyan A. Popov, Timothy P. Kurzweg

Drexel Univ. (USA)

Proc. SPIE 7907, Biomedical Applications of Light Scattering V, 790702 (February 04, 2011); doi:10.1117/12.875231
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From Conference Volume 7907

  • Biomedical Applications of Light Scattering V
  • Adam P. Wax; Vadim Backman
  • San Francisco, California, USA | January 22, 2011

abstract

White light spectroscopy has the potential to be used as an optical biopsy method, as backscattered light data can be related to the cellular nucleus size. In this paper, we compare experimental backscattering results against the general Mie theory simulations. Our experimental technique obtains results in terms of intensity vs. wavelength. We also use optical filters, to limit the source spectrum, and when converting the backscattered data into the Fourier domain, we obtain characteristic frequencies which describe the scatterer size. Phantom tissues, comprised of polystyrene spheres in a liquid or gel, are used for the experiments.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Kaloyan A. Popov and Timothy P. Kurzweg
"Theoretical and experimental comparison of tissue phantoms using white light spectroscopy", Proc. SPIE 7907, Biomedical Applications of Light Scattering V, 790702 (February 04, 2011); doi:10.1117/12.875231; http://dx.doi.org/10.1117/12.875231


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