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Proceedings Article

Differential spectral imaging with gold nanorod light scattering labels

[+] Author Affiliations
Le Qiu, Edward Vitkin, Lianyu Guo, Irving Itzkan, Lev T. Perelman

Harvard Univ. (USA)

Eugene B. Hanlon

Harvard Univ. (USA) and Dept. of Veterans Affairs (USA)

Proc. SPIE 7945, Quantum Sensing and Nanophotonic Devices VIII, 79452E (January 24, 2011); doi:10.1117/12.874240
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From Conference Volume 7945

  • Quantum Sensing and Nanophotonic Devices VIII
  • Manijeh Razeghi; Rengarajan Sudharsanan; Gail J. Brown
  • San Francisco, California | January 22, 2011

abstract

Gold nanorods have the potential to be employed as extremely bright molecular marker labels. However, samples containing a large number of gold nanorods usually exhibit relatively wide spectral lines. This linewidth limits the use of the nanorods since it would be rather difficult to image several types of nanorod markers simultaneously. We measured native scattering spectra of single gold nanorods with the CLASS microscope and found that single gold nanorods have a narrow spectrum as predicted by the theory. That suggests that nanorod-based molecular markers with controlled narrow aspect ratios should provide spectral lines sufficiently narrow for effective biomedical imaging.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Le Qiu ; Edward Vitkin ; Lianyu Guo ; Eugene B. Hanlon ; Irving Itzkan, et al.
"Differential spectral imaging with gold nanorod light scattering labels", Proc. SPIE 7945, Quantum Sensing and Nanophotonic Devices VIII, 79452E (January 24, 2011); doi:10.1117/12.874240; http://dx.doi.org/10.1117/12.874240


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