Acoustic microstreaming applied to batch micromixing

Richard Manasseh; Karolina Petkovic-Duran; Paul Tho; Yonggang Zhu; Andrew Ooi

doi:10.1117/12.668030

19 January 2006 Acoustic microstreaming applied to batch micromixing

Richard Manasseh, Karolina Petkovic-Duran, Paul Tho, Yonggang Zhu, Andrew Ooi

Proceedings Volume 6036, BioMEMS and Nanotechnology II; 603620 (2006) https://doi.org/10.1117/12.668030
Event: Microelectronics, MEMS, and Nanotechnology, 2005, Brisbane, Australia

Abstract

Experiments are presented in which acoustic microstreaming is investigated and applied to a batch micromixing case appropriate to a point-of-care pathology screening test. The flows presented can be created without complex engineering of contacts or surfaces in the microdevice, which could thus be made disposable. Fundamental flow patterns are measured with a micro-Particle-Image Velocimetry (micro-PIV) system, enabling a quantification of the fluiddynamical processes causing the flows. The design of micromixers based on this principle requires a quantification of the mixing. A simple technique based on digital image processing is presented that enables an assessment of the improvement in mixing due to acoustic microstreaming. The digital image processing technique developed was shown to be non-intrusive, convenient and able to generate useful quantitative data. Preliminary indications are that microstreaming can at least halve the time required to mix quantities of liquid typical of a point-of-care test, and significantly greater improvements seem feasible.

Citation Download Citation

Richard Manasseh, Karolina Petkovic-Duran, Paul Tho, Yonggang Zhu, and Andrew Ooi "Acoustic microstreaming applied to batch micromixing", Proc. SPIE 6036, BioMEMS and Nanotechnology II, 603620 (19 January 2006); https://doi.org/10.1117/12.668030

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