Direct reconstruction of T1 from k-space using a radial saturation-recovery sequence

Liyong Chen; Edward V. R. DiBella

doi:10.1117/12.878269

16 March 2011 Direct reconstruction of T₁ from k-space using a radial saturation-recovery sequence

Liyong Chen, Edward V. R. DiBella

Proceedings Volume 7961, Medical Imaging 2011: Physics of Medical Imaging; 79613U (2011) https://doi.org/10.1117/12.878269
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

Contrast agent concentration ([CA]) must be known accurately to quantify dynamic contrast-enhanced (DCE) MR imaging. Accurate concentrations can be obtained if the longitudinal relaxation rate constant T₁ is known both pre- and post-contrast injection. Post-contrast signal intensity in the images is often saturated and an approximation to T₁ can be difficult to obtain. One method that has been proposed for accurate T₁ estimation effectively acquires multiple images with different effective saturation recovery times (eSRTs) and fits the images to the equation for T₁ recovery to obtain T₁ values. This was done with a radial saturation-recovery sequence for 2D imaging of myocardial perfusion with DCE MRI. This multi-SRT method assumes that the signal intensity is constant for different readouts in each image. Here this assumption is not necessary as a model-based reconstruction method is proposed that directly reconstructs an image of T₁ values from k-space. The magnetization for each ray at each readout pulse is modeled in the reconstruction with Bloch equations. Computer simulations based on a 72 ray cardiac DCE MRI acquisition were used to test the method. The direct model-based reconstruction gave accurate T₁ values and was slightly more accurate than the multi-SRT method that used three sub-images.

Citation Download Citation

Liyong Chen and Edward V. R. DiBella "Direct reconstruction of T₁ from k-space using a radial saturation-recovery sequence", Proc. SPIE 7961, Medical Imaging 2011: Physics of Medical Imaging, 79613U (16 March 2011); https://doi.org/10.1117/12.878269

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