Towards a parts-based approach to sub-cortical brain structure parsing

Digvijay Gagneja; Caiming Xiong; Jason J. Corso

doi:10.1117/12.878170

14 March 2011 Towards a parts-based approach to sub-cortical brain structure parsing

Digvijay Gagneja, Caiming Xiong, Jason J. Corso

Proceedings Volume 7962, Medical Imaging 2011: Image Processing; 79623O (2011) https://doi.org/10.1117/12.878170
Event: SPIE Medical Imaging, 2011, Lake Buena Vista (Orlando), Florida, United States

Abstract

The automatic localization and segmentation, or parsing, of neuroanatomical brain structures is a key step in many neuroscience tasks. However, the inherent variability in these brain structures and their appearance continues to challenge medical image processing methods. The state of the art primarily relies upon local voxelbased morphometry, Markov random field, and probabilistic atlas based approaches, which limits the ability to explicitly capture the parts-based structure inherent in the brain. We propose a method that defines a principled parts-based representation of the sub-cortical brain structures. Our method is based on the pictorial structures model and jointly models the appearance of each part as well as the layout of the parts as a whole. Inference is cast as a maximum a posteriori problem and solved in a steepest-descent manner. Experimental results on a 28-case data set demonstrate high accuracy of our method and substantiate our claim that there is significant promise in a parts-based approach to modeling medical imaging structures.

Citation Download Citation

Digvijay Gagneja, Caiming Xiong, and Jason J. Corso "Towards a parts-based approach to sub-cortical brain structure parsing", Proc. SPIE 7962, Medical Imaging 2011: Image Processing, 79623O (14 March 2011); https://doi.org/10.1117/12.878170

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