Optical properties of human pulmonary artery tissue at Ti:Sapphire laser using inverse adding-doubling method in vitro

Huajiang Wei; Da Xing; Guoyong Wu; Huaiming Gu; Jianjun Lu; Ying Jin

doi:10.1117/12.710909

27 October 2006 Optical properties of human pulmonary artery tissue at Ti:Sapphire laser using inverse adding-doubling method in vitro

Huajiang Wei, Da Xing, Guoyong Wu, Huaiming Gu, Jianjun Lu, Ying Jin

Author Affiliations +

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 60471X (2006) https://doi.org/10.1117/12.710909
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

The purpose of present study is to determine and compare the optical properties of normal human pulmonary artery tissue in vitro at 650, 680, 710, 740, 780 nm wavelengths of Ti:Sapphire laser. The optical parameters of tissue samples were determined using a double integrating sphere set-up. The inverse Adding-doubling method was used to determine the optical properties from the measurements. The results of measurement showed that the absorption coefficients for pulmonary arteries increase with increase of laser wavelength, the maximum absorption coefficient is 0.277 mm^-1 at 780 nm, and the minimum absorption coefficient is 0.160 mm^-1 at 650nm, and the reduced scattering coefficients for pulmonary arteries increase with decrease of laser wavelength, the maximum reduced scattering coefficient is 48.8 mm^-1 at 650 urn, and the minimum reduced scattering coefficient is 13.3 mm^-1 at 780 nm. The optical penetration depths for pulmonary arteries increase with increase of laser wavelength, the maximum optical penetration depth is 0.298 mm at 780 nm, and the minimum optical penetration depth is 0.206 mm at 650 nm. The backscattered reflectances for normal human pulmonary arteries increase with decrease of laser wavelength, the maximum backscattered reflectance is 0.794 at 650 nm, and the minimum backscattered reflectance is 0.561 at 780 nm.

Citation Download Citation

Huajiang Wei, Da Xing, Guoyong Wu, Huaiming Gu, Jianjun Lu, and Ying Jin "Optical properties of human pulmonary artery tissue at Ti:Sapphire laser using inverse adding-doubling method in vitro", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60471X (27 October 2006); https://doi.org/10.1117/12.710909

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