Photobiomodulation on senescence

Timon Cheng-Yi Liu; Lei Cheng; Dong-Liang Rong; Xiao-Yang Xu; Li-Ping Cui; Jian Lu; Xiao-Yuan Deng; Song-Hao Liu

doi:10.1117/12.710692

27 October 2006 Photobiomodulation on senescence

Timon Cheng-Yi Liu, Lei Cheng, Dong-Liang Rong, Xiao-Yang Xu, Li-Ping Cui, Jian Lu, Xiao-Yuan Deng, Song-Hao Liu

Proceedings Volume 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine; 604732 (2006) https://doi.org/10.1117/12.710692
Event: Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2005, Tianjin, China

Abstract

Photobiomodulation (PBM) is an effect oflow intensity monochromatic light or laser irradiation (LIL) on biological systems. which stimulates or inhibits biological functions but does not result in irreducible damage. It has been observed that PBM can suppress cellular senescence, reverse skin photoageing and improve fibromyalgia. In this paper, the biological information model of photobiomodulation (BIMP) is used to discuss its mechanism. Cellular senescence can result from short, dysfunctional telomeres, oxidative stress, or oncogene expression, and may contribute to aging so that it can be seen as a decline of cellular function in which cAMP plays an important role, which provide a foundation for PBM on senescence since cellular senescence is a reasonable model of senescence and PBM is a cellular rehabilitation in which cAMP also plays an important role according to BIMP. The PBM in reversing skin photoageing and improving fibromyalgia are then discussed in detail.

Citation Download Citation

Timon Cheng-Yi Liu, Lei Cheng, Dong-Liang Rong, Xiao-Yang Xu, Li-Ping Cui, Jian Lu, Xiao-Yuan Deng, and Song-Hao Liu "Photobiomodulation on senescence", Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 604732 (27 October 2006); https://doi.org/10.1117/12.710692

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KEYWORDS

Proteins

Skin

Laser therapeutics

Brain

Data modeling

Laser irradiation

Systems modeling

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