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Proceedings Article

Advanced capabilities of the multimodal adaptive optics imager

[+] Author Affiliations
Daniel X. Hammer, R. D. Ferguson, Mircea Mujat, David P. Biss, Nicusor V. Iftimia, Ankit H. Patel, Emily Plumb

Physical Sciences Inc. (USA)

Melanie Campbell

Univ. of Waterloo (Canada)

Jennifer L. Norris, Alfredo Dubra

Univ. of Rochester (USA)

Toco Y. P. Chui, James D. Akula, Anne B. Fulton

Children's Hospital Boston (USA) and Harvard Medical School (USA)

Proc. SPIE 7885, Ophthalmic Technologies XXI, 78850A (February 16, 2011); doi:10.1117/12.876579
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From Conference Volume 7885

  • Ophthalmic Technologies XXI
  • Fabrice Manns; Per G. Söderberg; Arthur Ho
  • San Francisco, California, USA | January 22, 2011


We recently developed several versions of a multimodal adaptive optics (AO) retinal imager, which includes highresolution scanning laser ophthalmoscopy (SLO) and Fourier domain optical coherence tomography (FDOCT) imaging channels as well as an auxiliary wide-field line scanning ophthalmoscope (LSO). Some versions have also been equipped with a fluorescence channel and a retinal tracker. We describe the performance of three key features of the multimodal AO system including: simultaneous SLO/OCT imaging, which allows SLO/OCT co-registration; a small animal imaging port, which adjusts the beam diameter at the pupil from 7.5 to 2.5 mm for use with small animals ubiquitous in biological research or for extended depth-of-focus imaging in humans; and slow scan Doppler flowmetry imaging using the wide field auxiliary LSO imaging channel. The systems are currently deployed in several ophthalmology clinics and research laboratories and several investigations have commenced on patients with a variety of retinal diseases and animals in vision research.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

Daniel X. Hammer ; R. D. Ferguson ; Mircea Mujat ; David P. Biss ; Nicusor V. Iftimia, et al.
"Advanced capabilities of the multimodal adaptive optics imager", Proc. SPIE 7885, Ophthalmic Technologies XXI, 78850A (February 16, 2011); doi:10.1117/12.876579; http://dx.doi.org/10.1117/12.876579

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