Modification of a long period grating-based fiber optic for DNA biosensing

M. Sozzi; A. Cucinotta; R. Corradini; R. Marchelli; M. Konstantaki; S. Pissadakis; S. Selleri

doi:10.1117/12.874458

16 February 2011 Modification of a long period grating-based fiber optic for DNA biosensing

M. Sozzi, A. Cucinotta, R. Corradini, R. Marchelli, M. Konstantaki, S. Pissadakis, S. Selleri

Proceedings Volume 7894, Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI; 78940J (2011) https://doi.org/10.1117/12.874458
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

The feasibility of a biosensor for DNA label-free detection, based on long period fiber gratings, has been investigated. The surface of the grating has been functionalized with Peptide Nucleic Acid (PNA) probes. DNA strands, matched with the PNA probes, have been immobilized on the surface itself. The possibility of a resonant wavelength shift in the transmission spectrum due to the DNA capture will be discussed. The problem of reusing the sensor for multiple measurements will also be addressed.

Citation Download Citation

M. Sozzi, A. Cucinotta, R. Corradini, R. Marchelli, M. Konstantaki, S. Pissadakis, and S. Selleri "Modification of a long period grating-based fiber optic for DNA biosensing", Proc. SPIE 7894, Optical Fibers, Sensors, and Devices for Biomedical Diagnostics and Treatment XI, 78940J (16 February 2011); https://doi.org/10.1117/12.874458

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