Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Multi-site and multi-depth in vivo cancer localization enhancement after autofluorescence removal

[+] Author Affiliations
Anne-Sophie Montcuquet

CEA, LETI, MINATEC (France) and GIPSA-Lab., DIS (France)

Lionel Hervé, Fabrice Navarro, Jean-Marc Dinten

CEA, LETI, MINATEC (France)

Jérôme I. Mars

GIPSA-Lab., DIS (France)

Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78962S (February 17, 2011); doi:10.1117/12.874594
Text Size: A A A
From Conference Volume 7896

  • Optical Tomography and Spectroscopy of Tissue IX
  • Bruce J. Tromberg; Arjun G. Yodh; Mamoru Tamura; Eva M. Sevick-Muraca; Robert R. Alfano
  • San Francisco, California, USA | January 22, 2011

abstract

Fluorescence imaging in diffusive media locates tumors tagged by injected fluorescent markers in NIR wave-lengths. For deep embedded markers, natural autofluorescence of tissues comes to be a limiting factor to tumor detection and accurate FDOT reconstructions. A spectroscopic approach coupled with Non-negative Matrix Factorization source separation method is explored to discriminate fluorescence sources according to their fluorescence spectra and remove unwanted autofluorescence. We successfully removed autofluorescence from acquisitions on living mice with a single subcutaneous tumor or two capillary tubes inserted at different depths.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Anne-Sophie Montcuquet ; Lionel Hervé ; Fabrice Navarro ; Jean-Marc Dinten and Jérôme I. Mars
"Multi-site and multi-depth in vivo cancer localization enhancement after autofluorescence removal", Proc. SPIE 7896, Optical Tomography and Spectroscopy of Tissue IX, 78962S (February 17, 2011); doi:10.1117/12.874594; http://dx.doi.org/10.1117/12.874594


Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement


  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.