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Proceedings Article

Initial experiences in the photoacoustic detection of melanoma metastases in resected lymph nodes

[+] Author Affiliations
D. Grootendorst, J. Jose, P. Van der Jagt, W. Van der Weg, K. Nagel, W. Steenbergen, S. Manohar

Univ. of Twente (Netherlands)

M. Wouters, H. Van Boven

The Netherlands Cancer Institute (Netherlands)

T. G. Van Leeuwen

Univ. of Twente (Netherlands) and Univ. of Amsterdam (Netherlands)

T. Ruers

The Netherlands Cancer Institute (Netherlands) and Univ. of Twente (Netherlands)

Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 78993J (February 22, 2011); doi:10.1117/12.875456
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From Conference Volume 7899

  • Photons Plus Ultrasound: Imaging and Sensing 2011
  • Alexander A. Oraevsky; Lihong V. Wang
  • San Francisco, California, USA | January 22, 2011

abstract

Accurate lymph node analysis is essential to determine the prognosis and treatment of patients suffering from melanoma. The initial results of a tomographic photoacoustic modality to detect melanoma metastases in resected lymph nodes are presented based on phantom models and a human lymph node. The results show melanoma metastases detection is feasible and the setup is capable of distinguishing absorbing structures down to 1 mm. In addition, the use of longer laser wavelengths could result in an image containing a higher contrast ratio. Future research shall be focused on using the melanin characteristics to improve contrast and detection possibilities.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

Topics

Melanoma ; Lasers
Citation

D. Grootendorst ; J. Jose ; P. Van der Jagt ; W. Van der Weg ; K. Nagel, et al.
"Initial experiences in the photoacoustic detection of melanoma metastases in resected lymph nodes", Proc. SPIE 7899, Photons Plus Ultrasound: Imaging and Sensing 2011, 78993J (February 22, 2011); doi:10.1117/12.875456; http://dx.doi.org/10.1117/12.875456


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