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Proceedings Article

fMRI activation patterns in an analytic reasoning task: consistency with EEG source localization

[+] Author Affiliations
Bian Li, Kalyana C. Vasanta, Michael O'Boyle, Mary C. Baker, Brian Nutter, Sunanda Mitra

Texas Tech Univ. (USA)

Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76261T (March 09, 2010); doi:10.1117/12.845637
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From Conference Volume 7626

  • Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging
  • Robert C. Molthen; John B. Weaver
  • San Diego, California, USA | February 13, 2010

abstract

Functional magnetic resonance imaging (fMRI) is used to model brain activation patterns associated with various perceptual and cognitive processes as reflected by the hemodynamic (BOLD) response. While many sensory and motor tasks are associated with relatively simple activation patterns in localized regions, higher-order cognitive tasks may produce activity in many different brain areas involving complex neural circuitry. We applied a recently proposed probabilistic independent component analysis technique (PICA) to determine the true dimensionality of the fMRI data and used EEG localization to identify the common activated patterns (mapped as Brodmann areas) associated with a complex cognitive task like analytic reasoning. Our preliminary study suggests that a hybrid GLM/PICA analysis may reveal additional regions of activation (beyond simple GLM) that are consistent with electroencephalography (EEG) source localization patterns.

© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Bian Li ; Kalyana C. Vasanta ; Michael O'Boyle ; Mary C. Baker ; Brian Nutter, et al.
"fMRI activation patterns in an analytic reasoning task: consistency with EEG source localization", Proc. SPIE 7626, Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, 76261T (March 09, 2010); doi:10.1117/12.845637; http://dx.doi.org/10.1117/12.845637


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