Skin fluorescence model based on the Monte Carlo technique

Dmitry Y. Churmakov; Igor Vladislavovich Meglinski; Sergey A. Piletsky; Douglas A. Greenhalgh

doi:10.1117/12.518795

13 October 2003 Skin fluorescence model based on the Monte Carlo technique

Dmitry Y. Churmakov, Igor Vladislavovich Meglinski, Sergey A. Piletsky, Douglas A. Greenhalgh

Proceedings Volume 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV; (2003) https://doi.org/10.1117/12.518795
Event: Saratov Fall Meeting 2002 Laser Physics and Photonics, Spectroscopy, and Molecular Modeling III; Coherent Optics of Ordered and Random Media III, 2002, Saratov, Russian Federation

Abstract

The novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account spatial distribution of fluorophores following the collagen fibers packing, whereas in epidermis and stratum corneum the distribution of fluorophores assumed to be homogeneous. The results of simulation suggest that distribution of auto-fluorescence is significantly suppressed in the NIR spectral region, while fluorescence of sensor layer embedded in epidermis is localized at the adjusted depth. The model is also able to simulate the skin fluorescence spectra.

Citation Download Citation

Dmitry Y. Churmakov, Igor Vladislavovich Meglinski, Sergey A. Piletsky, and Douglas A. Greenhalgh "Skin fluorescence model based on the Monte Carlo technique", Proc. SPIE 5068, Saratov Fall Meeting 2002: Optical Technologies in Biophysics and Medicine IV, (13 October 2003); https://doi.org/10.1117/12.518795

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