Multidistance optical characterization of the female breast by time-resolved diffuse spectroscopy

Antonio Pifferi; Johannes Swartling; Eleonora Giambattistelli; Ekaterine Chikoidze; Alessandro Torricelli; Paola Taroni; Magnus Andersson; Anders Nilsson; Stefan Andersson-Engels

doi:10.1117/12.502076

15 October 2003 Multidistance optical characterization of the female breast by time-resolved diffuse spectroscopy

Antonio Pifferi, Johannes Swartling, Eleonora Giambattistelli, Ekaterine Chikoidze, Alessandro Torricelli, Paola Taroni, Magnus Andersson, Anders Nilsson, Stefan Andersson-Engels

Author Affiliations +

Proceedings Volume 5138, Photon Migration and Diffuse-Light Imaging; (2003) https://doi.org/10.1117/12.502076
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

Two systems for time-resolved diffuse spectroscopy were used for the optical characterization of the female breast in 4 volunteers. A first system was a compact laser diode instrument operated at 660 and 785 nm, while the second one was a broadband laboratory set-up based on mode-locked lasers tunable in the 610-1000 nm range. Measurements were obtained both in transmittance and in reflectance geometry at 5 inter-fiber distances ranging from 1 to 4 cm at different locations on the breast. Distinct spectral features both in absorption and in scattering were observed among the 4 volunteers, and for each subject between reflectance and transmittance measurements. These differences are correlated with the abundance of the glandular tissue and blood absorption. Upon increasing the inter-fiber distance in reflectance, deeper tissue structures were investigated, generally resulting in higher water contribution.

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Antonio Pifferi, Johannes Swartling, Eleonora Giambattistelli, Ekaterine Chikoidze, Alessandro Torricelli, Paola Taroni, Magnus Andersson, Anders Nilsson, and Stefan Andersson-Engels "Multidistance optical characterization of the female breast by time-resolved diffuse spectroscopy", Proc. SPIE 5138, Photon Migration and Diffuse-Light Imaging, (15 October 2003); https://doi.org/10.1117/12.502076

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