Speckle-microscopy for blood flow measurements in the smallest microvessel

Sergey S. Ulyanov; Yulia Alexandzovna Ganilova

doi:10.1117/12.500259

9 October 2003 Speckle-microscopy for blood flow measurements in the smallest microvessel

Sergey S. Ulyanov, Yulia Alexandzovna Ganilova

Proceedings Volume 5139, Confocal, Multiphoton, and Nonlinear Microscopic Imaging; (2003) https://doi.org/10.1117/12.500259
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

The peculiarities of movement of red blood cells and blood plasma in very narrow capillaries are analyzed in this paper. Microvessels with diameter about the erythrocyte size are investigated in details. Spatial distributions of velocity of scatterers in such vessels are studied. Optical model of blood microflow in the smallest capillaries is developed. Process of diffraction of strongly focused laser beam from smallest blood vessel is considered. The shapes of spectra of scattering intensity fluctuations in speckle-microscope are studied. Relations between the spectral characteristics of dynamic speckles scattered from RBC, moving in blood plasma, and the hydrodynamic characteristics of microflow are found.

Citation Download Citation

Sergey S. Ulyanov and Yulia Alexandzovna Ganilova "Speckle-microscopy for blood flow measurements in the smallest microvessel", Proc. SPIE 5139, Confocal, Multiphoton, and Nonlinear Microscopic Imaging, (9 October 2003); https://doi.org/10.1117/12.500259

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