Cells and tissue imaging with digital holographic microscopy

Christian D. Depeursinge; Etienne Cuche; Tristan Colomb; Pia Dahlgren; Anca M. Marian; Frederic Montfort; Pierre Marquet; Pierre J. Magistretti

doi:10.1117/12.500899

14 October 2003 Cells and tissue imaging with digital holographic microscopy

Christian D. Depeursinge, Etienne Cuche, Tristan Colomb, Pia Dahlgren, Anca M. Marian, Frederic Montfort, Pierre Marquet, Pierre J. Magistretti

Author Affiliations +

Proceedings Volume 5143, Novel Optical Instrumentation for Biomedical Applications; (2003) https://doi.org/10.1117/12.500899
Event: European Conferences on Biomedical Optics 2003, 2003, Munich, Germany

Abstract

The aim of Optical Digital Holography, applied to cells and tissue imaging, is to provide an accurate 3D imaging of biologic materials, down to the microscopic scale. The method has been developed to yield a very precise determination of cells and tissues morphology. Targeted accuracies are in the sub-micron range and allow for the observation of very small movements and deformations, produced, in particular, by depolarization of excitable cells and their metabolic activities. Direct imaging of tissue structures by the newly developed digital holography is deemed to offer unique investigation means in biology and medicine and attractive diagnostic capabilities.

Citation Download Citation

Christian D. Depeursinge, Etienne Cuche, Tristan Colomb, Pia Dahlgren, Anca M. Marian, Frederic Montfort, Pierre Marquet, and Pierre J. Magistretti "Cells and tissue imaging with digital holographic microscopy", Proc. SPIE 5143, Novel Optical Instrumentation for Biomedical Applications, (14 October 2003); https://doi.org/10.1117/12.500899

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