Tissue differentiation by diffuse reflectance spectroscopy for automated oral and maxillofacial laser surgery: ex vivo pilot study

Azhar Zam; Florian Stelzle; Katja Tangermann-Gerk; Werner Adler; Emeka Nkenke; Michael Schmidt; Alexandre Douplik

doi:10.1117/12.841674

22 February 2010 Tissue differentiation by diffuse reflectance spectroscopy for automated oral and maxillofacial laser surgery: ex vivo pilot study

Azhar Zam, Florian Stelzle, Katja Tangermann-Gerk, Werner Adler, Emeka Nkenke, Michael Schmidt, Alexandre Douplik

Author Affiliations +

Proceedings Volume 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII; 755516 (2010) https://doi.org/10.1117/12.841674
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Remote laser surgery lacks of haptic feedback during the laser ablation of tissue. Hence, there is a risk of iatrogenic damage or destruction of anatomical structures like nerves or salivary glands. Diffuse reflectance spectroscopy provides a straightforward and simple approach for optical tissue differentiation. We measured diffuse reflectance from seven various tissue types ex vivo. We applied Linear Discriminant Analysis (LDA) to differentiate the seven tissue types and computed the area under the ROC curve (AUC). Special emphasis was taken on the identification of nerves and salivary glands as the most crucial tissue for maxillofacial surgery. The results show a promise for differentiating tissues as guidance for oral and maxillofacial laser surgery by means of diffuse reflectance.

Citation Download Citation

Azhar Zam, Florian Stelzle, Katja Tangermann-Gerk, Werner Adler, Emeka Nkenke, Michael Schmidt, and Alexandre Douplik "Tissue differentiation by diffuse reflectance spectroscopy for automated oral and maxillofacial laser surgery: ex vivo pilot study", Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 755516 (22 February 2010); https://doi.org/10.1117/12.841674

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