Solid state light engines for bioanalytical instruments and biomedical devices

Claudia B. Jaffe; Steven M. Jaffe

doi:10.1117/12.841055

26 February 2010 Solid state light engines for bioanalytical instruments and biomedical devices

Claudia B. Jaffe, Steven M. Jaffe

Proceedings Volume 7556, Design and Quality for Biomedical Technologies III; 75560Q (2010) https://doi.org/10.1117/12.841055
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Lighting subsystems to drive 21st century bioanalysis and biomedical diagnostics face stringent requirements. Industrywide demands for speed, accuracy and portability mean illumination must be intense as well as spectrally pure, switchable, stable, durable and inexpensive. Ideally a common lighting solution could service these needs for numerous research and clinical applications. While this is a noble objective, the current technology of arc lamps, lasers, LEDs and most recently light pipes have intrinsic spectral and angular traits that make a common solution untenable. Clearly a hybrid solution is required to service the varied needs of the life sciences. Any solution begins with a critical understanding of the instrument architecture and specifications for illumination regarding power, illumination area, illumination and emission wavelengths and numerical aperture. Optimizing signal to noise requires careful optimization of these parameters within the additional constraints of instrument footprint and cost. Often the illumination design process is confined to maximizing signal to noise without the ability to adjust any of the above parameters. A hybrid solution leverages the best of the existing lighting technologies. This paper will review the design process for this highly constrained, but typical optical optimization scenario for numerous bioanalytical instruments and biomedical devices.

Citation Download Citation

Claudia B. Jaffe and Steven M. Jaffe "Solid state light engines for bioanalytical instruments and biomedical devices", Proc. SPIE 7556, Design and Quality for Biomedical Technologies III, 75560Q (26 February 2010); https://doi.org/10.1117/12.841055

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