Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Plasmonic nanohole arrays for real-time multiplex biosensing

[+] Author Affiliations
Antoine Lesuffleur, Hyungsoon Im, Nathan C. Lindquist, Kwan Seop Lim, Sang-Hyun Oh

Univ. of Minnesota, Twin Cities (USA)

Proc. SPIE 7035, Biosensing, 703504 (August 29, 2008); doi:10.1117/12.794299
Text Size: A A A
From Conference Volume 7035

  • Biosensing
  • Manijeh Razeghi; Hooman Mohseni
  • San Diego, California, USA | August 10, 2008

abstract

Large-scale studies of biomolecular interactions required for proteome-level investigations can benefit from a new class of emerging surface plasmon resonance (SPR) sensors: nanohole arrays and surface plasmon (SP) enhanced optical transmission. In this paper we present a real-time, label-free multiplex SPR imaging sensor in a microarray format. The system presented is built around a low-cost microscope with laser illumination, integrated with microfluidics. The specific binding kinetics of biotin and streptavidin are measured from several sensing elements simultaneously, demonstrating the feasibility of using nanohole arrays as a high-throughput SPR microarray sensor.

© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Antoine Lesuffleur ; Hyungsoon Im ; Nathan C. Lindquist ; Kwan Seop Lim and Sang-Hyun Oh
"Plasmonic nanohole arrays for real-time multiplex biosensing", Proc. SPIE 7035, Biosensing, 703504 (August 29, 2008); doi:10.1117/12.794299; http://dx.doi.org/10.1117/12.794299


Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.