An optimal cloud-clearing method using collocated MODIS clear pixels is applied to AIRS partly cloudy radiance. Temperature and humidity profiles with 100 layers are retrieved from cloud-free and cloud-cleared AIRS radiance. Using these retrieved profiles, atmospheric environment parameters (include Convective Available Potential Energy, CAPE; Convective Inhibition, CIN) and instability indices (include K index, Lifted Index, Showalter Index) are calculated and compared with that calculated from AIRS and ATOVS operational products and ECMWF analysis fields. These different datasets have different spatial resolution (both in vertical and in horizontal) and spectral resolution. Results show that spatial resolution have obviously influence to the calculations, the lower spatial resolution is likely to have some small energy region lost or reduce the calculation precision. And the profiles derived from partly cloudy area are more meaningful to weather events. The CAPE values of typhoon rain region show differences to that of trough region.© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.