Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Noise model for microcalcification detection in reconstructed tomosynthesis slices

[+] Author Affiliations
Guido van Schie, Nico Karssemeijer

Radboud Univ. Nijmegen Medical Ctr. (Netherlands)

Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 72600M (March 03, 2009); doi:10.1117/12.810936
Text Size: A A A
From Conference Volume 7260

  • Medical Imaging 2009: Computer-Aided Diagnosis
  • Nico Karssemeijer; Maryellen L. Giger
  • Lake Buena Vista, FL | February 07, 2009

abstract

For the detection of microcalcifications, accurate noise estimation has shown to be an important step. In tomosynthesis, noise models have been proposed for projection data. However, it is expected that manufacturers of tomosynthesis systems will not store the raw projection images, but only the reconstructed volumes. We therefore investigated if and how signal dependent image noise can be modelled in the reconstructed volumes. For this research we used a dataset of 41 tomosynthesis volumes, of which 12 volumes contained a total of 20 microcalcification clusters. All volumes were acquired with a prototype of Sectra's photon-counting tomosynthesis system. Preliminary results show that image noise is signal dependent in a reconstructed volume, and that a model of this noise can be estimated from a volume at hand. Evaluation of the noise model was performed by using a basic microcalcification cluster detection algorithm that classifies voxels by using a threshold on a local contrast filter. Image noise was normalized by dividing local contrast in a voxel by the standard deviation of the estimated image noise in that voxel. FROC analysis shows that performance increases strongly, when we use our model to correct for signal dependent image noise in reconstructed volumes.

© (2009) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Guido van Schie and Nico Karssemeijer
"Noise model for microcalcification detection in reconstructed tomosynthesis slices", Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 72600M (March 03, 2009); doi:10.1117/12.810936; http://dx.doi.org/10.1117/12.810936


Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.