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A polarized light camera (polCAM) is being used to guide surgical excision of skin cancers. Preliminary results of a
clinical pilot study are presented. The polCAM uses linearly polarized light and acquires parallel- and cross-polarized
images, then the difference image (par - cross) subtracts the background diffusely scattered light and yields an image the
unveils the fabric of the skin. Cancer disrupts the complex pattern of this fabric, revealing the cancer margin.
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Steven L. Jacques, Ravikant Samatham, Scott Isenhath M.D., Ken Lee M.D., "Polarized light camera to guide surgical excision of skin cancers," Proc. SPIE 6842, Photonic Therapeutics and Diagnostics IV, 68420I (8 February 2008); https://doi.org/10.1117/12.761823